• TOMASZ OSMAŁEK, PhD, MSc

    osmalekActing Head of the Department of Pharmaceutical Technology

    Department of Pharmaceutical Technology

     

    email: tosmalek@ump.edu.pl
    phone: 61 854 66 60

     

    The scientific area concerns the technology of semi-solid dosage forms, such as hydrogels or organogels, prepared on both natural (gellan gum, Locust Bean gum, xanthan gum) or synthetic (poloxamers, polyacrylates) polymers. The main interests focus on rheology and texture analysis. Dr Osmałek has practical skills in drug permeation through artificial membranes and animal skin with application of Franz cells.

    Other interests focus on application of ionotropic gelation in drug encapsulation. Current experiments deal with application of gellan gum and its mixtures with various natural polysaccharides in production of hydrophillic matrices as carriers for NSAIDs in oral dosage forms with modified release.

    Earlier studies concerned application of novel macrocyclic compounds in the photodynamic therapy of localized tumors.

    Dr Osmałek has experience in photostability testing of drugs. He is keen on spectroscopic and chromatographic analysis.

    Most important publications:

    1. Tomasz Osmałek, Anna Froelich, Sylwia Tasarek: Application of gellan gum in pharmacy and medicine. Int. J. Pharm. 2014, 466, 328-334. DOI: 10.1016/j.ijpharm.2014.03.038
    2. Tomasz Gośliński, Tomasz Osmałek, Krystyna Konopka, Marcin Wierzchowski, Piotr Fita, Jadwiga Mielcarek: Photophysical properties and photocytotoxicity of novel phthalocyanines – potentially useful for their application in photodynamic therapy. Polyhedron2011, 30, 1538-1546. DOI: 10.1016/j.poly.2011.03.003
    3. Anna Froelich, Tomasz Osmałek, Paweł Kunstman, Rafał Roszak, Wojciech Białas: Rheological and textural properties of micremulsion-based polymer gels with indomethacin. Drug Dev. Ind. Pharm. 2016, 42, 854-861. DOI: 10.3109/03639045.2015.1066799
    4. Tomasz Osmałek, Bartłomiej Milanowski, Froelich Anna, Sylwia Górska, Wojciech Białas, Mirosław Szybowicz, Marcin Kapela: Novel organogels for topical delivery of naproxen: design, physicochemical characteristics and in vitro drug permeation.Pharm. Dev. Technol. 2016, 20, 1-16. DOI: 10.3109/10837450.2015.1135342

    Current collaborations:

    • Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences
    • Faculty of Technical Physic, Poznan University of Technology
    • Center of Bioimmobilisation and Innovative Packaging Materials, Faculty of Food Sciences and Fisheries, West Pomeranian University of Technology, Szczecin