• Research interests

    The research interest of the Department lie in:

    • preformulation studies of active pharmaceutical ingredients and drug dosage forms (including assessment of physicochemical properties, particle size analysis, compatibility and stability studies, specific and apparent dissolution rates, rheological and texture properties)
    • development of advanced drug delivery systems (polymer- or lipid-based nano- and microparticles for oral or topical and transfollicular administration, drug loaded electrospun scaffolds for tissue engineering of vascular grafts, mesoporous drug-carrier system for enhanced delivery of poorly water-soluble drugs, microemulsions, hydrogels)
    • formulation computer aided design (DoE for optimization of drug formulation and evaluation of dosage forms based on advanced statistical analysis) and new process technologies (continuous manufacturing)
    • biopharmaceutical evaluation of drug dosage forms performance (using flow-through cell apparatus, biphasic systems, Franz cells, in vitro-in vivo correlation)
    • the use of qualitative methods and multimethodology in the field of pharmaceutical sciences
    • pharmaceutical care and interprofessional collaboration with health care professionals aimed to improve safety of patients therapy

     

    The Department of Pharmaceutical Technology is equipped with:

    • Christ Epsilon 2-4 LSCplus benchtop freeze dryer with LPCplus software
    • Mastersizer 3000 laser particle size analyzer with HydroSight, Hydro MV, Hydro SV and Aero S dispersion units
    • LabCompanion TH-ICH-800 pharmaceutical stability & photostability test chamber
    • Fully automated Shimadzu Nexera i-series LC-2040C 3D ultra high pressure liquid chromatograph with diode array detector (UV-Vis) and LabSolutions software
    • Gas Chromatograph Agilent 6890N with MS detector Agilent 5973N and ChemStation software
    • Shimadzu UV-2401PC UV-Vis recording spectrophotometer
    • Erweka DT60 dissolution apparatus (USP I & II) equipped with rotating disk (Wood apparatus) and stationary disk apparatus for intrinsic dissolution testing
    • Semi-automated on/off line SOTAX CE-7 Smart flow-through cell dissolution apparatus (USP IV) with SOTAX CP 7-35 piston pump, SOTAX C615 fraction collector and Thermo Evolution 300 UV-Vis on-line spectrophotometer and WinSOTAX plus and Thermo Vision Pro software
    • GastroPlus Software with IVIVCPlus Module and Additional Dosage Routes Module (includes dermal and ocular models)
    • Heat block module with six vertical jacketed Franz diffusion cells with stirrers & heaters (Permegear Inc., Hellertown, PA)
    • Rheometer Brookfield R/S Plus CP
    • Anton-Paar viscosimeter
    • Osmometr MARCEL OS3000
    • Buchi rotavapor R-215/V advance with vacuum pump and vacuum controller
    • Optical microscop with Motic camera
    • Homogenizers. mixers and stirrers
    • Radwag and Mettler electronic balances